Endocrine Abstracts

A 41-year-old woman was referred with 9 months history of secondary amenorrhoea and galactorrhoea. She was otherwise well and not taking any medications. Biochemical evaluation showed prolactin 2000 mU/l but otherwise unremarkable. Pituitary MRI revealed a 30 mm pituitary lesion with right cavernous sinus invasion, presumed to be a craniopharyngioma due to the presence of calcification. Surgical intervention was recommended, but the patient declined. She was commenced on caber...

The commonest cause of acquired hypopituitarism is a benign pituitary adenoma. However, in patients with non-pituitary malignancy different diagnoses need to be considered. We describe three oncology patients presenting with hypopituitarism and/or a pituitary mass where the cause was related either to malignant disease or its treatment.Case 1: A 56-year-old man with known metastatic melanoma presented with increasing lethargy. Investigation showed a larg...